Article
The sak1+ gene of Schizosaccharomyces pombe encodes an RFX family DNA-binding protein that positively regulates cyclic AMP-dependent protein kinase-mediated exit from the mitotic cell cycle.
Molecular and cellular biology - 1 Mar 1995
Wu S Y, McLeod M
Abstract excerpt
In Schizosaccharomyces pombe, meiosis is initiated by conditions of nutrient deprivation. Mutations in genes encoding elements of the cyclic AMP-dependent protein kinase (cAPK) pathway interfere with meiosis. Loss-of-function alleles of genes that stimulate the activity of cAPK allow cells to byp...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cell Cycle
- Cell Cycle Proteins
- Cloning, Molecular
- Cyclic AMP-Dependent Protein Kinases
- DNA-Binding Proteins
- Genes, Fungal
- Genotype
- Homeostasis
- Meiosis
- Mitosis
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Phenotype
- Plasmids
- Regulatory Factor X Transcription Factors