Article
PGF2 alpha activation of Na/H antiporter and ammoniagenesis in parent/variant LLC-PK1 cells.
Kidney international - 1 Oct 1994
Sahai A, Fadda G Z, Sandler R S, Tannen R L
Abstract excerpt
A novel variant of the LLC-PK1 cell line was used to examine directly the mechanism whereby PGF2 alpha and TPA inhibit renal ammoniagenesis. The variant cells, which exhibit a growth pattern and morphology similar to the parent cell line, were isolated by a self selection process utilizing long-t...
Topics
- Alanine
- Ammonia
- Animals
- Biological Transport, Active
- Dinoprost
- Enzyme Activation
- Genetic Variation
- Glucose
- Hydrogen-Ion Concentration
- LLC-PK1 Cells
- Protein Kinase C
- Sodium
- Sodium-Hydrogen Exchangers