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Article

Selection of variant hepatoma cells in liver-specific growth media: regulation at the mRNA level.

Differentiation; research in biological diversity - 1 May 1992

Armbruster L, Cavard C, Briand P, Bertolotti R

Abstract excerpt

Three liver-specific growth media, respectively free of arginine (Arg-), tyrosine (Tyr-) and glucose (G-), have been used to characterize cells of the rat H4IIEC3, human HepG2 and mouse BW hepatoma lines. Cells of clone FaO, a derivative of line H4IIEC3, freely grew in Tyr- and G- media, and gave rise to stable variants in Arg- conditions. Cells of line HepG2 and clone BWTG3, a derivative of line BW, degenerated...

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Identifiers

PMID: 1322334
DOI: 10.1111/j.1432-0436.1992.tb00482.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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