Article
The CLS2 gene encodes a protein with multiple membrane-spanning domains that is important Ca2+ tolerance in yeast.
Molecular & general genetics : MGG - 6 Feb 1995
Takita Y, Ohya Y, Anraku Y
Abstract excerpt
Genetic screening of Saccharomyces cerevisiae mutants defective in Ca2+ homeostasis identified cls2, which exhibits a specific Ca(2+)-sensitive growth phenotype. We describe here the CLS2 gene and a multicopy suppressor (named BCL21, for bypass of CLS2) of the cls2 mutation. The CLS2 gene encodes...
Topics
- Amino Acid Sequence
- Base Sequence
- Calcium
- Calcium-Binding Proteins
- Cloning, Molecular
- Endoplasmic Reticulum
- Fungal Proteins
- Genes, Fungal
- Genes, Suppressor
- Genetic Complementation Test
- Glycosyltransferases
- Membrane Proteins
- Models, Biological
- Molecular Sequence Data
- Mutation
- Repressor Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins