The PMR2 gene cluster encodes functionally distinct isoforms of a putative Na+ pump in the yeast plasma membrane.

doi:10.1002/j.1460-2075.1995.tb00059.x

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Article

The PMR2 gene cluster encodes functionally distinct isoforms of a putative Na+ pump in the yeast plasma membrane.

The EMBO journal - 15 Aug 1995

Wieland J, Nitsche A M, Strayle J, Steiner H, Rudolph H K

Abstract excerpt

We report a structural and functional analysis of the PMR2 gene cluster in yeast. We found that several strains of Saccharomyces cerevisiae contain multiple PMR2 genes repeated in tandem, whereas most phylogenetically related yeasts appear to possess only a single PMR2 gene. This unusual tandem array of nearly identical genes encodes putative ion pumps involved in Na+ tolerance. Pmr2a and Pmr2b, the proteins...

Topics

Adenosine Triphosphatases
Calcineurin
Calmodulin
Calmodulin-Binding Proteins
Cation Transport Proteins
Cell Fractionation
Cell Membrane
Enzyme Induction
Genes, Fungal
Ion Transport
Isoenzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lithium

Multigene Family

Mutation

Phosphoprotein Phosphatases

Promoter Regions, Genetic

RNA, Fungal

RNA, Messenger

Source

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Identifiers

PMID: 7664728
DOI: 10.1002/j.1460-2075.1995.tb00059.x
PMCID: PMC394466

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7664728-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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