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Article

[Apolipoprotein E4 and late-onset Alzheimer's disease].

Nihon rinsho. Japanese journal of clinical medicine - 1 Dec 1994

Tamaoka A

Abstract excerpt

Apolipoprotein E [APOE for protein; APOE for gene] is a 34 kDa plasma protein involved in cholesterol transport. In addition to hepatic cells, glial cells in the nervous system also produce APOE, which is postulated to be involved in the growth and repair of the nervous system during development or after injury. The APOE immunoreactivity was associated with amyloid both in senile plaques and cerebral blood...

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Source

Identifiers

PMID: 7853720

Genes

APOE
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Apolipoprotein E4 and late-onset Alzheimer's disease].PMID 7853720Read ↗

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Apolipoprotein E and Alzheimer disease: an update on genetic and functional analyses.Semantic proximity Read ↗

[Alzheimer disease: hypotheses implicating apolipoproteins E].Semantic proximity Read ↗

[Apolipoprotein E genotype as a risk factor in Japanese patients with early-onset and late-onset Alzheimer's disease].Semantic proximity Read ↗

Human apolipoprotein E: the Alzheimer's disease connection.Semantic proximity Read ↗

Apolipoprotein E and Alzheimer disease.Semantic proximity Read ↗

Expanding the association between the APOE gene and the risk of Alzheimer's disease: possible roles for APOE promoter polymorphisms and alterations in APOE transcription.Semantic proximity Read ↗

Curious Dichotomies of Apolipoprotein E Function in Alzheimer’s Disease and Cancer—One Explanatory Mechanism of Inverse Disease Associations?Semantic proximity Read ↗

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