Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation and characterization of a Bacillus subtilis secA mutant allele conferring resistance to sodium azide.

FEMS microbiology letters - 15 Dec 1994

Klein M, Hofmann B, Klose M, Freudl R

Abstract excerpt

A mutation has been isolated in the Bacillus subtilis secA gene (secA10) which allows cell growth and residual protein translocation in the presence of 1.5 mM sodium azide. Besides conferring resistance to sodium azide, the corresponding SecA10 mutant protein, in which glutamic acid at position 338 has been changed to glycine, seems to possess a secretion defect even in the absence of azide. In addition, the...

Topics

Azides
Bacillus subtilis
Bacterial Proteins
Base Sequence
Blotting, Western
DNA Probes
Drug Resistance, Microbial
Molecular Sequence Data
Mutation
Sodium Azide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7851746
DOI: 10.1111/j.1574-6968.1994.tb07314.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7851746-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation and characterization of a Bacillus subtilis secA mutant allele conferring resistance to sodium azide.PMID 7851746Read ↗

Mutations conferring resistance to azide in Escherichia coli occur primarily in the secA gene.Semantic proximity Read ↗

Suppression of signal sequence defects and azide resistance in Escherichia coli commonly result from the same mutations in secA.Semantic proximity Read ↗

Mutations that confer resistance to sodium azide affect the levels of two physiological isoforms of SecA in Escherichia coli.Semantic proximity Read ↗

Azide-resistant mutants of Escherichia coli alter the SecA protein, an azide-sensitive component of the protein export machinery.Semantic proximity Read ↗

Characterization of the secA gene of Streptomyces lividans encoding a protein translocase which complements and Escherichia coli mutant defective in the ATPase activity of SecA.Semantic proximity Read ↗

Identification of a Bacillus subtilis secretion mutant using a beta-galactosidase screening procedure.Semantic proximity Read ↗

Lysine 106 of the putative catalytic ATP-binding site of the Bacillus subtilis SecA protein is required for functional complementation of Escherichia coli secA mutants in vivo.Semantic proximity Read ↗

Isolation and analysis of dominant secA mutations in Escherichia coli.Semantic proximity Read ↗

Temperature-sensitive mutations in various genes of Escherichia coli K12 can be suppressed by the ssrA gene for 10Sa RNA (tmRNA).Semantic proximity Read ↗

Isolation and characterization of mutations in the gene encoding an endogenous Bacillus subtilis beta-galactosidase and its regulator.Semantic proximity Read ↗

Functional characterization of the Staphylococcus carnosus SecA protein in Escherichia coli and Bacillus subtilis secA mutant strains.Semantic proximity Read ↗

Expression and characterisation in E. coli of mutant forms of saporin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.