Article
Mutations conferring resistance to azide in Escherichia coli occur primarily in the secA gene.
Journal of bacteriology - 1 Nov 1990
Fortin Y, Phoenix P, Drapeau G R
Abstract excerpt
Mutant strains of Escherichia coli were screened for the ability to grow on L agar plates containing 3.4 or 4.6 mM sodium azide. Most mutants had mutations located in the leucine region, presumably at the azi locus. Two of these mutants were found to have a mutation in the secA gene, but expressi...
Topics
- Adenosine Triphosphatases
- Azides
- Bacterial Proteins
- DNA, Bacterial
- Drug Resistance, Microbial
- Escherichia coli
- Escherichia coli Proteins
- Genes, Bacterial
- Membrane Transport Proteins
- Mutation
- Phenotype
- R Factors
- Restriction Mapping
- SEC Translocation Channels
- SecA Proteins
- Sodium Azide
- Suppression, Genetic