Article
Expression of platelet-derived growth factor-alpha receptor in human osteosarcoma is not a predictor of outcome.
Pathology - 1 Dec 2010
Sulzbacher Irene, Birner Peter, Dominkus Martin, Pichlhofer Bettina, Mazal Peter R
Abstract excerpt
AIMS: The aims of this study were to examine the prognostic relevance of platelet-derived growth factor-α receptor (PDGFRA) expression in human osteosarcomas and to evaluate the mutation status of exon 12 and exon 18 of the PDGFRA gene. METHODS: PDGFRA expression was examined in 100 human osteosarcomas by immunohistochemistry using paraffin embedded tumour tissues, and capillary sequencing of genomic DNA was...
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