Article
DNA methylation and cancer.
Human molecular genetics - 1 Jan 1994
Laird P W, Jaenisch R
Abstract excerpt
Changes in the pattern of DNA methylation have been a consistent finding in cancer cells. The mostly descriptive nature of these studies and the fact that both hypo- and hypermethylation have been observed at various loci have made it difficult to assess whether these changes are causally involve...
Topics
- Animals
- Cell Transformation, Neoplastic
- DNA Modification Methylases
- DNA, Neoplasm
- Gene Expression
- Humans
- Methylation
- Mutation
- Neoplasms