Article
DNA methylation and cancer.
Human molecular genetics - 1 Jan 1994
Laird P W, Jaenisch R
Abstract excerpt
Changes in the pattern of DNA methylation have been a consistent finding in cancer cells. The mostly descriptive nature of these studies and the fact that both hypo- and hypermethylation have been observed at various loci have made it difficult to assess whether these changes are causally involved in the transformation process or whether they reflect the altered physiology of rapidly dividing cancer cells. It is...
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