DNA Methylation: An Alternative Pathway to Cancer

doi:10.1097/00000658-200107000-00003

Article

DNA Methylation: An Alternative Pathway to Cancer

1 Jul 2001

Abstract excerpt

OBJECTIVE: To provide an introduction to the concept of DNA methylation and its function in normal cells, and to explain the possible mechanisms as to how abnormalities in this phenomenon can relate to carcinogenesis. The clinical implications with reference to common malignancies encountered in surgical practice are discussed. SUMMARY BACKGROUND DATA: Methylation of DNA is a heritable, enzyme-induced...

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