DNA methylation and carcinogenesis.

doi:10.1023/a:1010249510906

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Article

DNA methylation and carcinogenesis.

Biochemistry. Biokhimiia - 1 Mar 2001

Lichtenstein A V, Kisseljova N P

Abstract excerpt

In the world of easy things truth is opposed to lie; in the world of complicated things one profound truth is opposed to another not less profound than the first. Neils Bohr The hypothesis of the exclusively genetic origin of cancer ("cancer is a disease of genes, a tumor without any damage to the genome does not exist") dominated in the oncology until recently. A considerable amount of data confirming this...

Topics

Aging
Alleles
Animals
Chromatin
CpG Islands
DNA (Cytosine-5-)-Methyltransferases
DNA Damage
DNA Methylation
Gene Silencing
Genes, Suppressor
Genome, Human
Genomic Imprinting
Histones
Humans
Models, Genetic
Mutation
Neoplasms

Source

Open in PubMed

Identifiers

PMID: 11333147
DOI: 10.1023/a:1010249510906

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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