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Article

Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17)

15 Feb 1995

Abstract excerpt

Analysis of a variant translocation t(11;17) in a case of acute promyelocytic leukemia (APL) led to discovery of a novel zinc finger gene, PLZF, fused to the retinoic acid receptor-alpha (RAR alpha) gene. We reviewed the clinical and molecular features of five additional patients with t(11;17)-associated APL. The clinical course of three patients was characterized by early death and three experienced disseminated...

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Identifiers

PMID: 7849296
DOI: 10.1182/blood.v85.4.1083.bloodjournal8541083

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Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17)PMID 7849296Read ↗

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