Article
Detection of PML-RAR alpha fusion transcript in Ph positive leukemia with acute promyelocytic phenotype lacking the t(15;17) cytogenetic abnormality.
Cancer genetics and cytogenetics - 1 Apr 1995
Emilia G, Marasca R, Longo G, Ferrari M G, Notohamiprodjo M, Temperani P, Sacchi S, Torelli G
Abstract excerpt
A 39-year-old woman was diagnosed with acute promyelocytic leukemia (APL) with disseminated intravascular coagulation syndrome. The hematologic examination showed a morphologic, cytochemical, and immunophenotypic picture typical of an APL, with a marked leukocytosis and a mixed population of hypergranular and microgranular promyelocytes. The cytogenetic analysis showed a 46,XX,t(9;22) karyotype, without any...
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