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Article

RARA and PML gene rearrangements in acute promyelocytic leukemia with complex translocations and atypical features.

Genes, chromosomes & cancer - 1 Jan 1994

McKinney C D, Golden W L, Gemma N W, Swerdlow S H, Williams M E

Abstract excerpt

The translocation t(15;17) associated with acute promyelocytic leukemia (APL) results in fusion of the retinoic acid receptor alpha (RARA) gene on chromosome 17 with the putative transcription factor gene, PML, on chromosome 15. We report three cases of APL with complex cytogenetic translocations and five cases with atypical phenotypic features with rearrangements within or adjacent to the second intron of the...

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Source

Identifiers

PMID: 7507700
DOI: 10.1002/gcc.2870090109

Genes

RARA
PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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RARA and PML gene rearrangements in acute promyelocytic leukemia with complex translocations and atypical features.PMID 7507700Read ↗

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PMLSemantic proximity Read ↗

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