Genotypic and Phenotypic Characteristics of Acute Promyelocytic Leukemia Translocation Variants.

doi:10.1016/j.hemonc.2020.05.007

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Genotypic and Phenotypic Characteristics of Acute Promyelocytic Leukemia Translocation Variants.

Hematology/oncology and stem cell therapy - 1 Dec 2020

Mannan Abdul, Muhsen Ibrahim N, Barragán Eva, Sanz Miguel A, Mohty Mohamad, Hashmi Shahrukh K, Aljurf Mahmoud

Abstract excerpt

Acute promyelocytic leukemia (APL) is a special disease entity of acute myeloid leukemia (AML). The clinical use of all-trans retinoic acid (ATRA) has transformed APL into the most curable form of AML. The majority of APL cases are characterized by the fusion gene PML-RARA. Although the PML-RARA fusion gene can be detected in almost all APL cases, translocation variants of APL have been reported. To date, this is...

Topics

Genotype
Humans
Leukemia, Promyelocytic, Acute
Neoplasm Proteins
Translocation, Genetic

Source

Open in PubMed

Identifiers

PMID: 32473106
DOI: 10.1016/j.hemonc.2020.05.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics