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Article

Roles of individual kringle domains in the functioning of positive and negative effectors of human plasminogen activation.

Biochemistry - 7 Feb 1995

Menhart N, Hoover G J, McCance S G, Castellino F J

Abstract excerpt

In order to identify the individual contributions of the kringle (K) domains of human plasminogen (Pg) to the epsilon-aminocaproic acid (EACA) induced stimulation of Pg activation by low-molecular-weight urokinase-type plasminogen activator (LMW-uPA) and inhibition of this same activation by Cl-, we constructed the most conservative recombinant- (r-) Pg mutants possible that would greatly reduce the strength of...

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PMID: 7849007
DOI: 10.1021/bi00005a003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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