Roles of individual kringle domains in the functioning of positive and negative effectors of human plasminogen activation.

doi:10.1021/bi00005a003

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Article

Roles of individual kringle domains in the functioning of positive and negative effectors of human plasminogen activation.

Biochemistry - 7 Feb 1995

Menhart N, Hoover G J, McCance S G, Castellino F J

Abstract excerpt

In order to identify the individual contributions of the kringle (K) domains of human plasminogen (Pg) to the epsilon-aminocaproic acid (EACA) induced stimulation of Pg activation by low-molecular-weight urokinase-type plasminogen activator (LMW-uPA) and inhibition of this same activation by Cl-,...

Topics

Aminocaproates
Base Sequence
Binding Sites
Chlorides
DNA, Complementary
Humans
Kringles
Molecular Sequence Data
Mutation
Plasminogen
Plasminogen Activators
Protein Conformation

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