Article
The kringle domains of human plasminogen.
Ciba Foundation symposium - 1 Jan 1997
Castellino F J, McCance S G
Abstract excerpt
The mature form of the zymogen, human plasminogen (HPlg), contains 791 amino acids present in a single polypeptide chain. The fibrinolytic enzyme, human plasmin (HPlm), is formed from HPlg as a result of activator-catalysed cleavage of the Arg561-Val562 peptide bond in HPlg. The resulting HPlm co...
Topics
- Amino Acid Sequence
- Crystallography, X-Ray
- Humans
- Kringles
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Plasminogen
- Protein Structure, Tertiary