Article
Interstitial deletion of 11q13 sequences in HeLa cells.
Genes, chromosomes & cancer - 1 Oct 2000
Srivatsan E S, Bengtsson U, Manickam P, Benyamini P, Chandrasekharappa S C, Sun C, Stanbridge E J, Redpath J L
Abstract excerpt
Previous cytogenetic and molecular genetic studies have shown that the HeLa (cervical carcinoma) cell line D98/AH-2 contains two apparently normal copies of chromosome 11 and additional 11q13-25 material translocated onto a chromosome 3 marker. To determine the 11q13 breakpoint, we performed fluorescence in situ hybridization (FISH) using 18 different 11q13 specific BAC (bacterial artificial chromosome) and...
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