Article
Regulation of expression of the cyclic nucleotide phosphodiesterase gene in phosphodiesterase inhibitor-negative mutants of Dictyostelium discoideum.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Jan 2000
Adames N R, Coukell M B, Wu L
Abstract excerpt
During early development of Dictyostelium discoideum, the enzyme cyclic nucleotide phosphodiesterase (PD) is produced at a low rate during the period its specific inhibitor (PDI) is being synthesized. In addition, PD gene expression is derepressed in the aggregation-deficient (Agg-), Pdi- mutant...
Topics
- 3',5'-Cyclic-AMP Phosphodiesterases
- Animals
- Cyclic AMP
- Dictyostelium
- Gene Expression Regulation
- Genetic Complementation Test
- Mutation
- Phenotype
- Phosphodiesterase Inhibitors
- RNA, Messenger