Apolipoprotein e4 allele and endothelium-dependent arterial dilation in Type 2 diabetes mellitus without angiopathy.

doi:10.1007/s00125-003-1060-5

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Article

Apolipoprotein e4 allele and endothelium-dependent arterial dilation in Type 2 diabetes mellitus without angiopathy.

Diabetologia - 1 Apr 2003

Guangda X, Yuhua W

Abstract excerpt

AIMS/HYPOTHESIS: Several studies have suggested a predisposing role of the e4 allele of apolipoprotein E (ApoE) in the development of atherosclerosis and cardiovascular disease in Type 2 diabetes. Therefore, we hypothesized that the e4 allele is also a risk factor for endothelial dysfunction. We attempted to assess whether Apo e4 allele is associated with endothelial dysfunction in the early stage of Type 2...

Topics

Adult
Aged
Alleles
Apolipoprotein E4
Apolipoproteins E
Brachial Artery
China
Diabetes Mellitus, Type 2
Diabetic Angiopathies
Endothelium, Vascular
Humans
Male
Middle Aged
Risk Factors
Vasodilation

Source

Open in PubMed

Identifiers

PMID: 12739024
DOI: 10.1007/s00125-003-1060-5

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