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Article

Genetic bases of the rifampin resistance phenotype in Brucella spp.

Journal of clinical microbiology - 1 Dec 2004

Marianelli Cinzia, Ciuchini Franco, Tarantino Michela, Pasquali Paolo, Adone Rosanna

Abstract excerpt

Rifampin is one of the most potent and broad-spectrum antibiotics against bacterial pathogens. Its bactericidal activity is due to its ability to bind to the beta subunit of the DNA-dependent RNA polymerase encoded by the rpoB gene. Mutations of the rpoB gene have been characterized in rifampin-resistant (Rif(r)) strains of Escherichia coli and Mycobacterium tuberculosis. The genetic bases of Rif(r) in Brucella...

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Identifiers

PMID: 15583262
DOI: 10.1128/JCM.42.12.5439-5443.2004
PMCID: PMC535235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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