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Article

FoxA1 and glucocorticoid receptor crosstalk via histone H4K16 acetylation at a hormone regulated enhancer.

Experimental cell research - 1 Jan 2012

Belikov Sergey, Holmqvist Per-Henrik, Astrand Carolina, Wrange Örjan

Abstract excerpt

The forkhead transcription factor FoxA1 participates in many gene regulatory events with steroid hormone receptors, one example being the integrated mouse mammary tumor virus (MMTV) promoter. Its enhancer harbors several FoxA1 binding sites. FoxA1 promotes glucocorticoid receptor (GR)-DNA binding and transcription. Here we analyze the regulatory capacity of GR, FoxA1 and hormone in quantitative terms when...

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Share to Acetylation
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gonadal Steroid Hormones

Share to Hepatocyte Nuclear Factor 3-alpha

Share to Mammary Tumor Virus, Mouse

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Share to Receptors, Glucocorticoid

Share to Xenopus laevis

Source

Identifiers

PMID: 22001115
DOI: 10.1016/j.yexcr.2011.09.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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