Article
A single element mediates glucocorticoid hormone response of HPV18 with no functional interactions with AP1 or hbrm.
Virology - 1 Mar 1996
Medina-Martinez O, Morales-Peza N, Yaniv M, García-Carrancá A, Thierry F
Abstract excerpt
We determined that the human papillomavirus type 18 (HPV18) regulatory region contains one functional GRE sequence that interacts with the glucocorticoid receptor. This sequence conferred a moderate hormonal activation to the HPV18 P105 promoter. Two modulators of glucocorticoid hormone activity,...
Topics
- Base Sequence
- Cell Line
- Cloning, Molecular
- Consensus Sequence
- DNA, Viral
- Gene Expression Regulation, Viral
- Glucocorticoids
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Papillomaviridae
- Receptors, Glucocorticoid
- Regulatory Sequences, Nucleic Acid
- Transcription Factor AP-1
- Transcription Factors
