Article
Radiation checkpoints in model systems.
International journal of radiation biology - 1 Dec 1994
Carr A M
Abstract excerpt
The response to DNA damaging agents includes a delay to progression through the cell cycle. Irradiation of premitotic cells causes a delay to mitosis and irradiation of G1 and S phase cells causes a delay to DNA synthesis. These delays have become known as checkpoints. The mechanisms that mediate the mitotic (or G2) checkpoint delay have recently come under study in yeast model systems. Work in the eukaryotic...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Cycle
- DNA Damage
- DNA, Fungal
- G1 Phase
- G2 Phase
- Molecular Sequence Data
- Mutation
- Saccharomyces
- Saccharomyces cerevisiae
- Sequence Homology, Amino Acid