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Article

Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis.

Genes & development - 15 Aug 1998

Freire R, Murguía J R, Tarsounas M, Lowndes N F, Moens P B, Jackson S P

Abstract excerpt

Preventing or delaying progress through the cell cycle in response to DNA damage is crucial for eukaryotic cells to allow the damage to be repaired and not incorporated irrevocably into daughter cells. Several genes involved in this process have been discovered in fission and budding yeast. Here, we report the identification of human and mouse homologs of the Schizosaccharomyces pombe DNA damage checkpoint...

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Source

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Identifiers

PMID: 9716408
DOI: 10.1101/gad.12.16.2560
PMCID: PMC317084

Genes

RAD17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human and mouse homologs of Schizosaccharomyces pombe rad1(+) and Saccharomyces cerevisiae RAD17: linkage to checkpoint control and mammalian meiosis.PMID 9716408Read ↗

RAD1, a human structural homolog of the Schizosaccharomyces pombe RAD1 cell cycle checkpoint gene.Semantic proximity Read ↗

HRad17 Colocalizes with NHP2L1 in the Nucleolus and Redistributes after UV IrradiationSemantic proximity Read ↗

Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination.Semantic proximity Read ↗

Cloning and characterization of RAD17, a gene controlling cell cycle responses to DNA damage in Saccharomyces cerevisiae.Semantic proximity Read ↗

The meiotic recombination checkpoint is regulated by checkpoint rad+ genes in fission yeast.Semantic proximity Read ↗

Mammalian Rad9 plays a role in telomere stability, S- and G2-phase-specific cell survival, and homologous recombinational repair.Semantic proximity Read ↗

The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint.Semantic proximity Read ↗

The Schizosaccharomyces pombe S-phase checkpoint differentiates between different types of DNA damage.Semantic proximity Read ↗

A recombination repair gene of Schizosaccharomyces pombe, rhp57, is a functional homolog of the Saccharomyces cerevisiae RAD57 gene and is phylogenetically related to the human XRCC3 gene.Semantic proximity Read ↗

Schizosaccharomyces pombe Rdh54 (TID1) acts with Rhp54 (RAD54) to repair meiotic double-strand breaks.Semantic proximity Read ↗

RACH2, a novel human gene that complements a fission yeast cell cycle checkpoint mutation.Semantic proximity Read ↗

Identification and characterization of new elements involved in checkpoint and feedback controls in fission yeast.Semantic proximity Read ↗

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