Analysis of hepatitis B precore region in serum and liver of chronic hepatitis B virus carriers.

doi:10.1016/s0168-8278(05)80313-7

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Article

Analysis of hepatitis B precore region in serum and liver of chronic hepatitis B virus carriers.

Journal of hepatology - 1 Sept 1994

López-Alcorocho J M, Moraleda G, Bartolomé J, Castillo I, Cotonat T, Aguilar J, Ortega E, Pons J A, Salmerón J, Vázquez-Iglesias J L

Abstract excerpt

Using an oligonucleotide hybridization assay we studied the prevalence of wild-type and the predominant pre-core mutant hepatitis B virus in serum and liver of 49 antibody to hepatitis B e antigen carriers and three hepatitis B e antigen positive patients. Of the 45 serum samples from the anti-HBe carriers analyzed (no serum sample was available in four patients), 36 (80%) had hepatitis B virus DNA. In 26 of...

Topics

Adolescent
Adult
Aged
Alanine Transaminase
Base Sequence
Carrier State
Child
Chronic Disease
DNA Primers
DNA, Viral
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Hepatitis B

Hepatitis B Antibodies

Hepatitis B Core Antigens

Hepatitis B e Antigens

Hepatitis B virus

Humans

Source

Open in PubMed

Identifiers

PMID: 7836704
DOI: 10.1016/s0168-8278(05)80313-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7836704-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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