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Article

Analysis of hepatitis B precore region in serum and liver of chronic hepatitis B virus carriers.

Journal of hepatology - 1 Sept 1994

López-Alcorocho J M, Moraleda G, Bartolomé J, Castillo I, Cotonat T, Aguilar J, Ortega E, Pons J A, Salmerón J, Vázquez-Iglesias J L

Abstract excerpt

Using an oligonucleotide hybridization assay we studied the prevalence of wild-type and the predominant pre-core mutant hepatitis B virus in serum and liver of 49 antibody to hepatitis B e antigen carriers and three hepatitis B e antigen positive patients. Of the 45 serum samples from the anti-HBe carriers analyzed (no serum sample was available in four patients), 36 (80%) had hepatitis B virus DNA. In 26 of...

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PMID: 7836704
DOI: 10.1016/s0168-8278(05)80313-7

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