Molecular analysis of mutations induced by chemical carcinogens in mammalian cells. I. The use of selectable gene loci.

Article

Molecular analysis of mutations induced by chemical carcinogens in mammalian cells. I. The use of selectable gene loci.

Annali dell'Istituto superiore di sanita - 1 Jan 1994

Fortini P, Dogliotti E

Abstract excerpt

Several lines of evidence indicate the important role of mutation in the process of carcinogenesis, however our understanding of the factors that influence the formation of mutation is still limited. Recent developments in the analysis of gene mutations at selectable loci in cultured mammalian ce...

Topics

Alkylating Agents
Animals
Benzo(a)pyrene
Carcinogens
Cells, Cultured
DNA Damage
DNA Repair
Mammals
Mutation

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