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Article

Regulation of c-ski transgene expression in developing and mature mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jan 1995

Leferovich J M, Lana D P, Sutrave P, Hughes S H, Kelly A M

Abstract excerpt

The control of c-ski transgene expression and muscle hypertrophy have been investigated in transgenic mice. In adult animals, the level of transgene expression is linked to the specialized phenotype of individual muscles, high levels occur in fast muscles and significantly lower levels in muscles with high metabolic activity (diaphragm, soleus). These findings have led us to propose that a threshold must be...

Topics

Aging
Animals
Animals, Newborn
DNA-Binding Proteins
Gene Expression Regulation
Mice
Mice, Transgenic
Muscle Development
Muscles
Myosins
Nervous System Physiological Phenomena

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Proto-Oncogene Proteins

RNA, Messenger

Thyroid Gland

Source

Open in PubMed Open full text

Identifiers

PMID: 7823166
PMCID: PMC6578338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7823166-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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