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Article

Transgenic remodeling of the regulatory myosin light chains in the mammalian heart.

Circulation research - 1 May 1997

Gulick J, Hewett T E, Klevitsky R, Buck S H, Moss R L, Robbins J

Abstract excerpt

The regulatory myosin light chain (MLC) regulates contraction in smooth muscle. However, its function in striated muscle remains obscure, and the different functional activities of the various isoforms that are expressed in the mammalian heart (ventricle- and atrium-specific MLC2) remain undefined. To begin to explore these issues, we used transgenesis to determine the feasibility of effecting a complete or...

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Identifiers

PMID: 9130446
DOI: 10.1161/01.res.80.5.655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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