Transgenic remodeling of the regulatory myosin light chains in the mammalian heart.

doi:10.1161/01.res.80.5.655

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Article

Transgenic remodeling of the regulatory myosin light chains in the mammalian heart.

Circulation research - 1 May 1997

Gulick J, Hewett T E, Klevitsky R, Buck S H, Moss R L, Robbins J

Abstract excerpt

The regulatory myosin light chain (MLC) regulates contraction in smooth muscle. However, its function in striated muscle remains obscure, and the different functional activities of the various isoforms that are expressed in the mammalian heart (ventricle- and atrium-specific MLC2) remain undefine...

Topics

Animals
Base Sequence
Electrophoresis
Genetic Variation
Heart
Heart Atria
Heart Ventricles
Heterozygote
Mice
Mice, Transgenic
Molecular Sequence Data
Muscle Proteins
Muscle, Skeletal
Myocardial Contraction
Myocardium
Myosin Light Chains
Polymerase Chain Reaction
Transgenes

Source

Open in PubMed

Identifiers

PMID: 9130446
DOI: 10.1161/01.res.80.5.655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9130446-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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