Article
The induction of skeletal muscle hypertrophy by a ski transgene is promoter-dependent.
Gene - 4 Jan 2000
Sutrave P, Leferovich J M, Kelly A M, Hughes S H
Abstract excerpt
The chicken c-ski gene expresses at least three alternatively spliced messages. Transgenic mice expressing proteins from cDNA corresponding to two of these messages (FB27 and FB29) under the control of a murine sarcoma virus (MSV) long terminal repeat (LTR) express the transgene in skeletal muscle and develop a muscular phenotype. Both a biologically active form of c-ski and the MSV LTR are required for the...
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