Article
Studies on the metabolism of retinol and retinol-binding protein in transthyretin-deficient mice produced by homologous recombination.
The Journal of biological chemistry - 13 Jan 1995
Wei S, Episkopou V, Piantedosi R, Maeda S, Shimada K, Gottesman M E, Blaner W S
Abstract excerpt
Tissue needs for retinoids are believed to be satisfied through the delivery in the circulation of retinol by its specific plasma transport protein, retinol-binding protein (RBP), which circulates as a 1-to-1 protein complex with transthyretin (TTR). The binding of RBP to TTR is thought to prevent filtration of retinol-RBP in the kidney and to play a role in secretion of RBP from hepatocytes. Recently a strain of...
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