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Article

Altered retinoid distribution in the repeated epilation (Er) mutant mouse.

Journal of craniofacial genetics and developmental biology - 1 Jan 2000

Jones A H, Lehman P, Dale B A

Abstract excerpt

The repeated epilation (Er) mutation in mice causes successive loss and regrowth of hair in heterozygotes (Er/+), and blocks orofacial development and epidermal differentiation in lethal homozygotes (Er/Er). Because the mutation affects a systemic factor, because the Er phenotypes resemble exposu...

Topics

Animals
Animals, Newborn
Female
Hair
Immunoblotting
Immunohistochemistry
Male
Mice
Mice, Inbred C57BL
Mutation
Organ Specificity
Phenotype
Rabbits

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Retinoids

Retinol-Binding Proteins

Retinol-Binding Proteins, Plasma

Skin

Thyroid Gland

Source

Identifiers

PMID: 1613075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1613075-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Click a neighbor to travelStep 1 · 12 closest

Altered retinoid distribution in the repeated epilation (Er) mutant mouse.PMID 1613075Read ↗

Repeated epilation: a genetic epidermal syndrome in mice.Semantic proximity Read ↗

Skin abnormalities generated by temporally controlled RXRalpha mutations in mouse epidermis.Semantic proximity Read ↗

Chromosomal localization of the retinol binding protein gene and its elimination as a candidate gene for the repeated epilation (Er) mutation in mice.Semantic proximity Read ↗

Pathways of vitamin A delivery to the embryo: insights from a new tunable model of embryonic vitamin A deficiency.Semantic proximity Read ↗

Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver.Semantic proximity Read ↗

Postnatal eye size in mice is controlled by SREBP2-mediated transcriptional repression of Lrp2 and Bmp2Semantic proximity Read ↗

Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth.Semantic proximity Read ↗

Increased sensitivity to two-stage skin carcinogenesis of mice heterozygous for the repeated epilation mutation (Er).Semantic proximity Read ↗

Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function.Semantic proximity Read ↗

Transplacental delivery of retinoid: the role of retinol-binding protein and lipoprotein retinyl esterSemantic proximity Read ↗

Dominant-negative retinoic acid receptors elicit epidermal defects through a non-canonical pathway.Semantic proximity Read ↗

Somatic ablation of the Lrat gene in the mouse retinal pigment epithelium drastically reduces its retinoid storage.Semantic proximity Read ↗

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