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Article

Transplacental delivery of retinoid: the role of retinol-binding protein and lipoprotein retinyl ester

21 Apr 2004

Abstract excerpt

Retinoids are required for normal embryonic development. Both embryonic retinoid deficiency and excess result in congenital malformations. There is little understanding of the physiology underlying retinoid transfer from the maternal circulation to the embryo. We now report studies that explore this process using retinol-binding protein-deficient (RBP-/-) mice and mice that express human RBP on the RBP-/-)...

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Identifiers

PMID: 14736708
DOI: 10.1152/ajpendo.00556.2003

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