Escalation of intake under intermittent ethanol access in diverse mouse genotypes.

doi:10.1111/j.1369-1600.2012.00481.x

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Article

Escalation of intake under intermittent ethanol access in diverse mouse genotypes.

Addiction biology - 1 May 2013

Rosenwasser Alan M, Fixaris Michael C, Crabbe John C, Brooks Peter C, Ascheid Sonja

Abstract excerpt

Experimental animals offered continuous 24-hour free choice access to ethanol rarely display voluntary ethanol consumption at levels sufficient to induce intoxication or to engender dependence. One of the simplest ways to increase voluntary ethanol intake is to impose temporal limitations on ethanol availability. Escalation of ethanol intake has been observed in both rats and mice under a variety of different...

Topics

Analysis of Variance
Animals
Binge Drinking
Central Nervous System Depressants
Ethanol
Genotype
Male
Mice
Mice, Inbred C57BL
Motor Activity
Substance Withdrawal Syndrome

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Identifiers

PMID: 22862671
DOI: 10.1111/j.1369-1600.2012.00481.x
PMCID: PMC3508291

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