Article
Ethanol self-administration is genetically independent of locomotor stimulation in fast and slow mice.
Alcohol (Fayetteville, N.Y.) - 1 Jan 2000
Sanchez F P, Dickenson L, George F R
Abstract excerpt
One substance abuse hypothesis proposes that rewarding effects of drugs are causally related to their psychostimulant effects. We examined this hypothesis by comparing operant self-administration of ethanol in mice selectively bred for either high (Fast) or low (Slow) locomotor stimulation response to ethanol. Mice were trained to lever press for ethanol using postprandial induction and were then tested over a...
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