Article
[The p53 gene and protein in bronchial carcinogenesis:from biological to clinical aspects].
Revue des maladies respiratoires - 1 Jan 1994
Zalcman G, Trédaniel J, Lechapt E, Lubin R, Soussi T, Hirsch A
Abstract excerpt
The p53 gene codes for a nuclear phosphoprotein which is capable of modulating the expression of certain genes implicated in the regulation of cell division. The mutation of an allele on the p53 gene with loss of the healthy allele, in different tissues such as lung, larynx, bladder, liver, skin, colon and breast, which may or may not be exposed to chemical or physical carcinogens (tobacco, radon, ultraviolet,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
