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Article

[Tumor suppressor gene p53. Theoretical principles and their significance for pathology].

Der Pathologe - 1 May 1996

Poremba C, Bankfalvi A, Dockhorn-Dworniczak B

Abstract excerpt

Mutations of the p53 tumor-suppressor gene are the most common genetic alterations in human cancer, found in approximately 50% of all tumors. The importance of p53 in human cancer attracts attention in molecular studies dealing with the pathogenesis, diagnosis and prognosis in tumor pathology. This review summarizes the current understanding of p53 both on the genetic and protein level. Frequency and spectrum of...

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Identifiers

PMID: 8710788
DOI: 10.1007/s002920050153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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