Article
Clinical applications of the p53 tumor suppressor gene.
Clinica chimica acta; international journal of clinical chemistry - 15 Jun 1995
Diamandis E P
Abstract excerpt
The interest on the p53 gene has grown enormously in the last 4 years. It is now known that p53 is directly involved in important cellular functions including regulation of the cell cycle, and that its alteration may be one of the important steps in the initiation of cancer. In this review I will cover briefly basic and clinical aspects related to the p53 gene and protein and explore ways of using the accumulated...
Topics
- Autoantibodies
- Genes, p53
- Humans
- Mutation
- Neoplasms
- Tumor Suppressor Protein p53
