Article
Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis.
The EMBO journal - 2 Dec 1996
Fang M, Kearns B G, Gedvilaite A, Kagiwada S, Kearns M, Fung M K, Bankaitis V A
Abstract excerpt
The yeast phosphatidylinositol transfer protein (Sec14p) is required for biogenesis of Golgi-derived transport vesicles and cell viability, and this essential Sec14p requirement is abrogated by inactivation of the CDP-choline pathway for phosphatidylcholine biosynthesis. These findings indicate t...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Carrier Proteins
- Cytidine Diphosphate Choline
- DNA Primers
- Fungal Proteins
- Golgi Apparatus
- Humans
- Membrane Proteins
- Phosphatidylinositols
- Phospholipid Transfer Proteins
- Polymerase Chain Reaction