Article
Mechanisms of light adaptation in Drosophila photoreceptors.
Current biology : CB - 12 Jul 2005
Gu Yuchun, Oberwinkler Johannes, Postma Marten, Hardie Roger C
Abstract excerpt
Phototransduction in Drosophila is mediated by a phospholipase C (PLC) cascade culminating in activation of transient receptor potential (TRP) channels. Ca(2+) influx via these channels is required for light adaptation, but although several molecular targets of Ca(2+)-dependent feedback have been identified, their contribution to adaptation is unclear. By manipulating cytosolic Ca(2+) via the Na(+)/Ca(2+)...
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