Article
Genetic alterations in a malignant schwannoma from a patient with neurofibromatosis (NF1).
Pathology, research and practice - 1 May 1993
Lothe R A, Saeter G, Danielsen H E, Stenwig A E, Høyheim B, O'Connell P, Børresen A L
Abstract excerpt
In a patient with neurofibromatosis (von Recklinghausen disease; NF1), normal lymphocytes, five cutaneous neurofibromas, and tumour tissue from a recurrence of a malignant schwannoma were analysed for genetic alterations. Eleven DNA markers located on chromosome 17 and nine randomly chosen markers representing chromosomes 1, 2, 3, 4, 5, 6, and 11, were analysed. High resolution Giemsa banding of lymphocytes...
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