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Article

Systematic structure-function analysis of the small GTPase Arf1 in yeast.

Molecular biology of the cell - 1 May 2002

Click Eleanor S, Stearns Tim, Botstein David

Abstract excerpt

Members of the ADP-ribosylation factor (Arf) family of small GTPases are implicated in vesicle traffic in the secretory pathway, although their precise function remains unclear. We generated a series of 23 clustered charge-to-alanine mutations in the Arf1 protein of Saccharomyces cerevisiae to determine the portions of this protein important for its function in cells. These mutants display a number of phenotypes,...

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Identifiers

PMID: 12006660
DOI: 10.1091/mbc.02-01-0007
PMCID: PMC111134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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