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Article

TAF(II)s mediate activation of transcription in the Drosophila embryo.

Cell - 27 Dec 1996

Sauer F, Wassarman D A, Rubin G M, Tjian R

Abstract excerpt

Mutations in the genes for two highly conserved TAFs, TAF(II)60 and TAF(II)110, reduce transcription of Bicoid-dependent target genes in vivo. By means of several distinct genetic test systems, specific activator-TAF interactions are shown to support both simple and synergistic enhancement of transcription in the embryo. These studies provide in vivo evidence that TAFs can serve as coactivators to receive...

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PMID: 8980233
DOI: 10.1016/s0092-8674(00)81822-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

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TAF(II)s mediate activation of transcription in the Drosophila embryo.PMID 8980233Read ↗

Developmental and transcriptional consequences of mutations in Drosophila TAF(II)60.Semantic proximity Read ↗

Mesoderm-determining transcription in Drosophila is alleviated by mutations in TAF(II)60 and TAF(II)110.Semantic proximity Read ↗

TAF250 is required for multiple developmental events in Drosophila.Semantic proximity Read ↗

The novel transcription factor e(y)2 interacts with TAF(II)40 and potentiates transcription activation on chromatin templates.Semantic proximity Read ↗

Drosophila TFIIA-S is up-regulated and required during Ras-mediated photoreceptor determination.Semantic proximity Read ↗

Gene enhancer of yellow 1 of Drosophila melanogaster codes for protein TAFII40.Semantic proximity Read ↗

Yeast TAF(II)90 is required for cell-cycle progression through G2/M but not for general transcription activation.Semantic proximity Read ↗

Histone-like TAFs are essential for transcription in vivo.Semantic proximity Read ↗

Genetic analysis of TAF68/61 reveals links to cell cycle regulators.Semantic proximity Read ↗

Two Novel <i>Drosophila</i> TAF<sub>II</sub>s Have Homology with Human TAF<sub>II</sub>30 and Are Differentially Regulated during DevelopmentSemantic proximity Read ↗

Mapping and functional characterization of the TAF11 interaction with TFIIA.Semantic proximity Read ↗

Developmental regulation of transcription by a tissue-specific TAF homolog.Semantic proximity Read ↗

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