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Article

[Synthesis and functional studies on nucleic acids. Problems related to synthetic ras genes].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan - 1 Oct 1994

Ohtsuka E

Abstract excerpt

Synthesis of a gene for an oncoprotein, ras p21 and its functions are described. Point mutations in hot spots of ras genes have been found in human cancer cells and produce activated p21 which result in transformation of cultured NIH3T3 cells. To produce normal and activated p21 in quantity for b...

Topics

Amino Acid Sequence
Animals
Base Sequence
DNA
Genes, Synthetic
Genes, ras
Humans
Molecular Sequence Data
Mutation
Oncogene Protein p21(ras)
RNA, Catalytic
Transformation, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7807379
DOI: 10.1248/yakushi1947.114.10_747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7807379-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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