Article
Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development.
The Journal of cell biology - 1 Dec 1994
Chen P, Ostrow B D, Tafuri S R, Chisholm R L
Abstract excerpt
Conventional myosin has two different light chains bound to the neck region of the molecule. It has been suggested that the light chains contribute to myosin function by providing structural support to the neck region, therefore amplifying the conformational changes in the head following ATP hydr...
Topics
- Actins
- Animals
- Blotting, Western
- Calcium-Transporting ATPases
- Cell Aggregation
- Cell Division
- Cytoskeleton
- DNA, Protozoan
- DNA, Recombinant
- Dictyostelium
- Fluorescent Antibody Technique
- Genes, Protozoan
- Microscopy, Fluorescence
- Mutagenesis
- Myosins
- Phenotype
- Transformation, Genetic