Single-headed myosin II acts as a dominant negative mutation in Dictyostelium.

doi:10.1073/pnas.92.18.8244

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Article

Single-headed myosin II acts as a dominant negative mutation in Dictyostelium.

Proceedings of the National Academy of Sciences of the United States of America - 29 Aug 1995

Burns C G, Larochelle D A, Erickson H, Reedy M, De Lozanne A

Abstract excerpt

Conventional myosin II is an essential protein for cytokinesis, capping of cell surface receptors, and development of Dictyostelium cells. Myosin II also plays an important role in the polarization and movement of cells. All conventional myosins are double-headed molecules but the significance of...

Topics

Amino Acid Sequence
Animals
Dictyostelium
Genes, Dominant
Molecular Sequence Data
Mutation
Myosins
Phenotype
Phosphorylation

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