Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation and characterization of Dictyostelium cells deficient in a myosin I heavy chain isoform.

The Journal of cell biology - 1 Jun 1990

Jung G, Hammer J A

Abstract excerpt

Motile activities such as chemotaxis and phagocytosis, which occur in Dictyostelium cells lacking myosin II, may be dependent upon myosin I. To begin to explore this possibility, we have engineered a disruption of the Dictyostelium myosin I heavy chain (DMIHC) gene described recently (Jung, G., C. L. Saxe III, A. R. Kimmel, and J. A. Hammer III. 1989. Proc. Natl. Acad. Sci. USA. 86:6186-6190). The...

Topics

Chromosome Mapping
Dictyostelium
Gene Expression
Genetic Vectors
Immunoblotting
Myosins
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2141028
DOI: 10.1083/jcb.110.6.1955
PMCID: PMC2116136

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2141028-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation and characterization of Dictyostelium cells deficient in a myosin I heavy chain isoform.PMID 2141028Read ↗

Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions.Semantic proximity Read ↗

Molecular genetic truncation analysis of filament assembly and phosphorylation domains of Dictyostelium myosin heavy chain.Semantic proximity Read ↗

Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant.Semantic proximity Read ↗

Stage-specific requirement for myosin II during Dictyostelium development.Semantic proximity Read ↗

F-actin distribution of Dictyostelium myosin I double mutants.Semantic proximity Read ↗

Targeted disruption of the Dictyostelium myosin essential light chain gene produces cells defective in cytokinesis and morphogenesis.Semantic proximity Read ↗

Genetically engineered truncated myosin in Dictyostelium: the carboxyl-terminal regulatory domain is not required for the developmental cycle.Semantic proximity Read ↗

The role of myosin heavy chain phosphorylation in Dictyostelium motility, chemotaxis and F-actin localization.Semantic proximity Read ↗

Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development.Semantic proximity Read ↗

Cell-type-specific rescue of myosin function during Dictyostelium development defines two distinct cell movements required for culmination.Semantic proximity Read ↗

Complementation of myosin null mutants in Dictyostelium discoideum by direct functional selection.Semantic proximity Read ↗

Genetic techniques for enhancing biochemical and structural characterization of Dictyostelium myosin II.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.