Article
An Escherichia coli gene (FabZ) encoding (3R)-hydroxymyristoyl acyl carrier protein dehydrase. Relation to fabA and suppression of mutations in lipid A biosynthesis.
The Journal of biological chemistry - 30 Dec 1994
Mohan S, Kelly T M, Eveland S S, Raetz C R, Anderson M S
Abstract excerpt
Escherichia coli strain SM101 harbors a temperature-sensitive allele (lpxA2) of the gene encoding UDP-Glc-NAc acyltransferase (the first enzyme of the lipid A pathway). SM101 is temperature-sensitive for lipid A biosynthesis and growth. To determine whether or not E. coli mutants lacking lipid A can be isolated, we examined temperature-resistant revertants of SM101. All regained the ability to synthesize lipid A....
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Escherichia coli
- Fatty Acid Synthase, Type II
- Fimbriae Proteins
- Gene Expression Regulation, Bacterial
- Gene Expression Regulation, Enzymologic
- Genes, Bacterial