The firA gene of Escherichia coli encodes UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase. The third step of endotoxin biosynthesis.

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Article

The firA gene of Escherichia coli encodes UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase. The third step of endotoxin biosynthesis.

The Journal of biological chemistry - 15 Sept 1993

Kelly T M, Stachula S A, Raetz C R, Anderson M S

Abstract excerpt

The possibility that the firA gene of Escherichia coli (Dicker, I. B., and Seetharam, S. (1991) Mol. Microbiol. 6, 817-823) might function in lipid A biosynthesis was examined based on its homology to the lpxA gene, which encodes UDP-N-acetylglucosamine O-acyl-transferase, the first enzyme in lip...

Topics

Acyltransferases
Amino Acid Sequence
Bacterial Proteins
Base Sequence
Chromosome Mapping
Chromosomes, Bacterial
Endotoxins
Escherichia coli
Gene Expression
Genes, Bacterial
Genotype
Kinetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipid A

Molecular Sequence Data

Oligodeoxyribonucleotides

Phosphorus Radioisotopes

Sequence Homology, Amino Acid

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 8366125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8366125-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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